It did look promising for the Gunners at one stage after Alexandre Lacazette gave Arsène Wenger's men the lead in the 14th minute with a good finish at the end of a well-worked move.
So with the Magpies breaking their Arsenal hoodoo, who were the winners and losers?
With a nod perhaps to next season, Arsenal manager Arsene Wenger paired Lacazette and Pierre-Emerick Aubameyang up front and they combined for the goal, with Aubameyang clipping over a cross that Lacazette finished on the slide.
Matt Ritchie scored the victor as the Magpies went past the 40-point mark, 13 clear of the relegation zone.
With Joe Willock starting against Newcastle this afternoon, he became only the fourth player to be born after Arsene Wenger took charge of his first Arsenal match - joining Reiss Nelson, Ainsley Maitland-Niles and Eddie Nketiah. As long as Southampton doesn't win the FA Cup, seventh place will earn Arsenal a Europa League qualifying spot.
Therefore, the game ended in yet another away loss for the Gunners, who have yet to even take a point away from home in the league in 2018, while the win all but means that Newcastle are safe from relegation this season.
Jonjo Shelvey's rich vein of form continued as he displayed a range of passing which helped to keep Newcastle in a game which might otherwise have run away from them.
It was Arsenal's 11th defeat of the season.
With Atletico Madrid to face in the semi-finals of the Europa League, Wenger will have to tighten things up at the back. "Today we didn't play fantastic football because we played an wonderful team, but you have to manage how you play and compete for the win".
Rafael Benitez admitted he could not have dreamt Newcastle would smash through the Premier League's 40-point barrier with five games to spare.
His recent form has been insatiable and should the midfield marvel continue to impress on Tyneside, then a place on the plane to Russian Federation for the World Cup this summer may not be out of the question for Shelvey. For a second time in a week he was beaten by a run at the near post with Perez this time the benefactor.
He added: 'Children were harmed - some physically, some sexually, some were introduced to drugs for the first time'. Thousands of teachers gathered at the Capitol to ask lawmakers to override the vetoes.
And Seymour told Leighton Smith that rather than protecting the environment, the move will actually have the opposite affect. But Ms Ardern said no-one would be losing their job as a result of the move.
Rupani said the government was always committed to protect the rights, given in the Constitution, of any community. It also referenced how Prime Minister Shri Narendra Modi had been inspired by the life and message of Dr Ambedkar.
The agency said it has not identified specific farms or companies that grew, supplied and distributed the contaminated vegetables. It is advised if you have store bought romaine lettuce to throw it away, even if you have already eaten some and not gotten sick.
That win gave her Indian teammates the confidence they can beat Singapore, the dominant force at Commonwealth Games . Also, this was for the first time where both the men's and the women's team bagged top honour in table tennis event.
RCB bowlers bowled with a game plan and apart from Yadav (3/23), all other bowlers chipped in and restricted Punjab to 155. A ball earlier, he had pulled Yadav for a four and was expecting the same from him the next ball.
In Oladipo they have a player capable of taking over a game, but James knows the ropes better than anyone this time of year. Of the Pacers top 10 contributors in minutes per game, only Cory Joseph and Lance Stephenson have played all 82 games.
The problem is, when a fourth line is creating the best scoring opportunities, you're typically doing very little offensively. As coaches, sometimes you take it for granted because we've seen it a number of times over the course of a few seasons.
Saina wins first game in gold medal match
Coming back, there was no stopping the Indian who raced to a 17-13 lead before closing the game in 21 minutes. Her win over Singapore great Feng Tianwei in the women's singles rubber of the gold medal tie was remarkable.
Yankees show little fight until ninth, lose to Red Sox
Red Sox first baseman Hanley Ramirez has left their game against the New York Yankees after he was hit by a pitch on his left arm. Boston placed LHP Bobby Poyner (strained hamstring) on the 10-day disabled list and recalled Walden from Triple-A Pawtucket.
The Truth About Trump's War on Amazon and the US Postal Service
Amazon and other companies, like FedEx and UPS, drop off sorted packages, and a postal worker delivers them on their usual route. Trump has also gone after Bezos personally and accused The Washington Post , which he owns, of being Amazon's "chief lobbyist".
Weather turning ugly as blizzard conditions approach
A wildfire in northwestern Oklahoma burned more than 120,000 acres Thursday and forced hundreds of people to evacuate their homes. Strong winds may make travel hard and unsafe . "So we do have a lot of moisture with it, and a lot of energy", Beitlich said.